Many agents of the IMRB were present on this Tuesday, January 21, 2020 for the greetings of our director Jorge Boczkowski in the Alain Harf room of the Faculty of Health of Créteil. Following the evaluation of our Centre by the HCERES from 13 to 15 March 2019, and whose results were very positive, […]Read more
Using cold and liquid ventilation to reduce the risk of after-effects following cardiac arrest: Researchers from ENVA, UPEC, Inserm and the Mondor Institute are at the forefront of this new technique.
46,000 people suffer cardiac arrest every year in France. Researchers from EnvA, the University of Paris Est Créteil, Inserm and the Mondor Institute for Biomedical Research, including Professor Renaud Tissier (Bijan Ghaleh team), and also Professor Philippe Micheau from the University of Sherbrooke in Canada, are proposing a new approach to better manage them and […]Read more
HIV vaccine clinical batch release: a major milestone for the Vaccine Research Institute’s vaccine development program.
Le Vaccine Research Institute (VRI) et l’ANRS sont heureux d’annoncer avec leurs partenaires Novasep et GTP Technology, la production et la libération du premier lot clinique d’un vaccin anti-VIH pour une première administration chez l’Homme. Le partenariat établi entre le VRI, l’ANRS, Novasep et GTP Technology en septembre 2016 a permis la […]Read more
Marielle Bréau former doctoral student of Serge Adnot’s team, winner of the Thesis Prize of the University of Paris-Est for the Doctoral School of Life Sciences and Health!
Marielle Bréau, a post-doctoral fellow at the Marseille cancer research centre, received the thesis prize from the University of Paris Est for the Doctoral School of Life and Health Sciences (SVS) on 5 November. This prize rewards his work during his PhD at the IMRB on “Cellular senescence and pathophysiology of chronic lung diseases: […]Read more
EUR LIVE “Trajectories and Vulnerability in Health”, one of UPEC’s University Research Schools projects, has been selected from 81 applications!
Under the chairmanship of Sir Malcolm Grant (recently President of the NHS England) and on the proposal of an international jury, the Prime Minister has selected 24 winners of the second wave of calls for projects “University Schools of Research“. Among them, EUR LIVE aims to address the problem of vulnerability by […]Read more
Publication of an article resulting from the collaboration of teams 3 and 18, in the excellent journal Gastroenterology!
M. Panel, D. MOrin, B. Ghaleh (équipe 3), I. Ruiz, H. Ahmed-Belkacem, J-M. Pawlotsky Hepatic ischemia is a complication of liver surgery that involves mitochondrial dysfunction resulting from the opening of mitochondrial permeability transition pores (mPTP). Cyclophiline D (PPIF or CypD) is a peptidyl-prolyl cis-trans isomerase that regulates the mPTP opening in the […]Read more
Frédérique Vidal, Minister of Higher Education, Research and Innovation, Emmanuelle Wargon, Secretary of State to the Minister of State, Minister of Ecological and Solidarity Transition, Agnès Pannier-Runacher, Secretary of State to the Minister of the Economy and Finance and Guillaume Boudy, Secretary General for Investment, distinguished 140 winners of the i-Lab and i-Nov Innovation Competitions, […]Read more
Cindy Orvain, team 16 of the IMRB, has recently obtained her thesis with success. It is on the cover of the internal magazine Inserm In Vivo* in June 2019. She recounts her journey as part of the 16 team she joined in 2015, where she studies the regulation of effective responses of T cells and […]Read more
Virginie Firlej (team 7), co-author with the CEA of Fontenay-aux_Roses, of a publication in the journal Nature of May 15 on neural progenitors of the central nervous system expressing double-cortin (DCX+), infiltrate prostate tumors and metastases, and initiate neurogenesis.
Autonomic nerve fibres in the tumour microenvironment regulate cancer initiation and dissemination, but how nerves emerge in tumours is currently unknown. Here we show that neural progenitors from the central nervous system that express doublecortin (DCX+) infiltrate prostate tumours and metastases, in which they initiate neurogenesis. In mouse models of prostate cancer, oscillations of […]Read more
Publication of a recent study published in Cell Stem Cell by Team 10 on the protective effect of PAX3 in response to dioxin exposure!
A recent study conducted by Audrey Der Vartanian (post-doctoral researcher) and Marianne Gervais-Taurel (CNRS researcher) in the team of Pr. Frédéric Relaix (Team 10, IMRB) reveals that the transcription factor PAX3 protects a subpopulation of adult skeletal muscle stem cells in response to chronic exposure to an environmental pollutant, dioxin, with harmful effects on health. […]Read more
Professor Vincent Audard (Nephrology and Transplantation Department, IMRB Team 21) as coordinator of the Rare Disease Reference Centre (CRMR) “Idiopathic Nephrotic Syndrome” was presented on Tuesday 12 March 2019 during the Kidney Foundation gala (http://www.fondation-du-rein.org/) a research grant to set up within the 5 CRMR sites (Henri Mondor coordinator site, Robert Débré, Necker, Tenon and […]Read more
Stéphane Palfi, team 14, guest on France Culture of the program “Matières à penser” devoted to “Grands espoirs en médecine”, Friday, February 15, 2019 at 10:15 pm!
Stéphane Palfi, head of Team 14 at our Institute, will be René Frydman’s guest on France Culture’s “Matières à penser” program, dedicated this week to high hopes in medicine and new ideas. He will talk about the promises of stimulating the spinal cord to make paralytics walk again, but also about possible difficulties of experimentation […]Read more
It is around a cake of kings and surrounded by a large number of members of the IMRB, Mrs Camille Chaudonneret our regional delegate of Inserm Paris 6, as well as some members of the Faculty of Medicine, that our director Jorge Boczkowski presented us his wishes and encouragement for this year 2019 which […]Read more
Carbon monoxide-induced metabolic switch in adipocytes improves insulin resistance in obese mice JCI Insight, November 15, 2018
A recent study conducted by Laura Braud, post-doctoral fellow in the Equipe directed by Roberto Motterlini (Equipe 12, IMRB), reveals that carbon monoxide (CO) improves insulin resistance and glucose metabolism in obese mice. The study appeared in the November issue of JCI Insight (Link: https://insight.jci.org/articles/view/123485). Braud and colleagues showed that oral administration of a compound […]Read more
EHVA launches a clinical trial to test a combination of therapeutic vaccines and an immunotherapy drug!
EHVA (European HIV Vaccine Alliance) announces the start of the EHVA T01 / ANRS VRI05 trial. EHVA-T01 / ANRS VRI05, a double-blind, randomized, Phase I/II trial, will evaluate the combination of experimental HIV therapeutic vaccines and an investigational immunotherapy drug in people living with HIV in six European countries – France, Germany, Spain, Italy, […]Read more
Congratulations to Claire Leibler, doctoral student of Team 21, winner of the 2017 Thesis Prize of the University of Paris-Est for ED SVS and the Aguirre/Robin Prize!
Claire Leibler, a nephrologist specializing in kidney transplantation, received the thesis prize from the University of Paris Est for the Doctoral School of Life and Health Sciences (SVS) on November 6. On December 2, she will also receive the Aguirre-Basulado / Robin Prize for Medicine, one of the fifty solemn prizes awarded by the Chancellery […]Read more