December 18 2021

Publication of an article and editorial in the journal JACC on the beneficial effect of Ryanodine receptor stabilization to improve left ventricular function in young dogs with Duchenne muscular dystrophy

Duchenne muscular dystrophy is associated with progressive deterioration of left ventricular function. The golden retriever canine model of muscular dystrophy (GRMD) recapitulates the pathology and clinical manifestations of Duchenne muscular dystrophy. It is important to note that they develop progressive left ventricular dysfunction at an early age.   In an article (with an editorial) published […]

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December 13 2021

Publication of a study in Clinical Cancer Research on the identification of two main immune subtypes of cHCC-CCA (“Immune High” and “Immune Low”) in patients with mixed hepatocholangiocarcinoma tumors

Mixed hepatocholangiocarcinoma (cHCC-CCA) tumors are rare primary liver cancers associated with a very poor prognosis. They are resistant to all conventional cancer therapies and are characterized by the presence of a dual phenotype of both hepatocyte and biliary tumors. In a study conducted by Cong Trung Nguyen, Stefano Caruso and Pascale Maillé under the supervision […]

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December 7 2021

Congratulations to Marion LEBOYER who wins the Inserm Grand Prix 2021!

The Grand Prize recognizes the innovative nature of his work, particularly on bipolar disorders, schizophrenia and autism spectrum disorders. Just forty years ago, Marion Leboyer encountered psychiatry “by chance,” she admits. When choosing internship positions, I didn’t get the one for neuro-pediatric resuscitation, and I took what seemed to me to be the furthest from […]

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November 26 2021

Congratulations to Yannis Djeffal, PhD student in Frédéric Relaix’s team who receives the Line Pomaret-Delalande 2021 Prize (FRM Prize) for his thesis work on the understanding of the biology of muscle satellite cells

This prize, worth €105,600, comes from a donation by Sylvie Pomaret. Created in memory of his mother, it is intended to support research on rare diseases and finances a 3-year doctoral contract. Yannis Djeffal is pursuing a double degree in Medicine and Science. He is doing his doctoral work in science under the joint supervision […]

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October 1 2021

Congratulations to Pauline Favre, newly recruited as a research fellow at Inserm in Marion Leboyer’s team!

Pauline Favre is a neuropsychologist, recently recruited at INSERM as a CRCN researcher in Marion Leboyer’s team “Neuropsychiatrie Translationnelle”.   She did her PhD in Psychology, Cognitive Sciences and Neurocognition at the University of Grenoble (LPNC – CNRS) on the brain correlates of bipolar disorder and the contribution of psychoeducation in the treatment of this […]

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September 28 2021

Covid-19: a study of the effectiveness of immune memory after mRNA vaccination to recognize SARS-CoV2 variants

Teams from Henri-Mondor Hospital AP-HP and Université Paris-Est Créteil, Inserm, CNRS, Université de Paris, Institut Necker-Enfants malades, and Institut Pasteur have conducted research on the ability of the immune memory generated after mRNA vaccination to recognize and neutralize SARS-CoV-2 variants.   One of the main coordinators of this study is Professor Matthieu Mahévas of the […]

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September 13 2021

Innovative vaccine candidate effective against disease in preclinical models

Researchers from Inserm and the University of Paris-Est Créteil at the Vaccine Research Institute (VRI), the CEA and the University of Paris-Saclay have developed a vaccine targeting key cells of the immune system, the dendritic cells.   It has been shown to be effective in preclinical models, inducing a protective immune response against the virus. […]

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June 4 2021

Congratulations to Carole Hénique-Gréciet (Sahali Team, Head of the IMRB Scientific Animation Committee) for her nomination to the Institut Universitaire de France!

By order of the Minister of Higher Education, Research and Innovation dated May 12, 2021, Carole Hénique-Gréciet (Sahali Team, Head of the Scientific Facilitation Committee of the IMRB) is appointed Junior Member of the Institut Universitaire de France (IUF) as of October 1, 2021.   The mission of the IUF is to promote the development […]

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May 21 2021

Céline Colnot’s group, Relaix team, published in Nature Communications on May 17, a study on the role of muscle in bone regeneration.

  Bone regeneration involves activation of tissue resident stem/progenitor cells. This study reveals that skeletal stem/progenitor cells are not only recruited from bone tissues (i.e. bone marrow and periosteum) but also from adjacent skeletal muscle.   Using in vivo lineage tracing and scRNAseq, the results show that mesenchymal progenitors from skeletal muscle mediate the fibrotic […]

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May 10 2021

Congratulations to Marie Tamagne, Pirenne team, honored by the EFS for her recent publications in two internationally renowned journals!

Marie Tamagne is an engineering assistant in France Pirenne’s “Transfusion and red blood cell diseases” team. She has been honored by the EFS for her recent work on the mechanisms of post-transfusion alloimmunization against red blood cells, which she is carrying out in the “Genetics and Immunity of Transfusion” group directed by Benoît Vingert. Assisted […]

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May 5 2021

EUR LIVE Graduate School of Research: first series of videos on EUR-LIVE’s scientific activity

In partnership with INSERM and CNRS, “EUR-LIVE” is a project designed within the framework of the “Investissements d’Avenir” (PIA) projects and supported by the ANR. EUR-LIVE (ANR-18-EUR-0011) aims to combine the know-how and research contributions of multiple disciplines to address vulnerability in all its facets, by creating a University Research School at UPEC.   See […]

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April 29 2021

Interview with Prof. Marion Leboyer (IMRB-U955, Leboyer team) for the Institut Montaigne*: The mental health of young French people is deteriorating according to an IPSOS survey conducted for the FondaMental Foundation**.

Conducted in December 2020, the IPSOS survey reveals that since the beginning of the health crisis, young people, women and the most precarious are suffering the full impact of this crisis, whose figures speak for themselves: – 31% of the population has a suspicion of generalized anxiety disorder. Among 22-24 year olds, the figures rise […]

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April 28 2021

UPEC launches its partnership foundation

“Acting together for a fairer and more enlightened society” is the vision of the new UPEC Foundation, created by the university and four co-founders (BNP Paribas, Thales, the Seine-et-Marne Departmental Council and Agefiph). The foundation aims to provide new resources and support the ambitions of the university, which is committed to the promotion of excellence […]

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April 15 2021

Rituximab-resistant memory B cells contribute to relapse in adult patients with immunological thrombocytopenia: A study led by Professor Matthieu Mahevas, Pirenne team at IMRB and published in Science Translational Medicine

Teams led by Prof. Matthieu Mahévas of the Reference Center for Autoimmune Cytopenias in Adults and the Mondor Institute of Biomedical Research (Henri-Mondor Hospital AP-HP/Inserm/University of Paris-Est Créteil), Prof. Jean-Claude Weill and Dr. Claude-Agnès Reynaud at the Institut Necker-Enfants Malades (Inserm/CNRS/University of Paris) studied the presence of self-reactive memory B lymphocytes before and after rituximab […]

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April 1 2021

COVID-19: Discovery of a new variant at the Henri-Mondor Hospital by the teams of the virology laboratory, the “Genomics” platform, and the IMRB

Teams from the virology laboratory (Dr Slim FOURATI) and the “Genomics” platform (Dr Christophe RODRIGUEZ) of the Henri-Mondor Hospital AP-HP, Inserm and the University Paris-Est Créteil (Institut Mondor de Recherche Biomédicale, U955 Inserm-Université Paris-Est Créteil), under the direction of Professor Jean-Michel PAWLOTSKY, have discovered a new variant of SARS-CoV-2, the virus responsible for COVID-19.   […]

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