Frédérique Vidal, Minister of Higher Education, Research and Innovation, Emmanuelle Wargon, Secretary of State to the Minister of State, Minister of Ecological and Solidarity Transition, Agnès Pannier-Runacher, Secretary of State to the Minister of the Economy and Finance and Guillaume Boudy, Secretary General for Investment, distinguished 140 winners of the i-Lab and i-Nov Innovation Competitions, […]Read more
Cindy Orvain, team 16 of the IMRB, has recently obtained her thesis with success. It is on the cover of the internal magazine Inserm In Vivo* in June 2019. She recounts her journey as part of the 16 team she joined in 2015, where she studies the regulation of effective responses of T cells and […]Read more
Virginie Firlej (team 7), co-author with the CEA of Fontenay-aux_Roses, of a publication in the journal Nature of May 15 on neural progenitors of the central nervous system expressing double-cortin (DCX+), infiltrate prostate tumors and metastases, and initiate neurogenesis.
Autonomic nerve fibres in the tumour microenvironment regulate cancer initiation and dissemination, but how nerves emerge in tumours is currently unknown. Here we show that neural progenitors from the central nervous system that express doublecortin (DCX+) infiltrate prostate tumours and metastases, in which they initiate neurogenesis. In mouse models of prostate cancer, oscillations of […]Read more
Publication of a recent study published in Cell Stem Cell by Team 10 on the protective effect of PAX3 in response to dioxin exposure!
A recent study conducted by Audrey Der Vartanian (post-doctoral researcher) and Marianne Gervais-Taurel (CNRS researcher) in the team of Pr. Frédéric Relaix (Team 10, IMRB) reveals that the transcription factor PAX3 protects a subpopulation of adult skeletal muscle stem cells in response to chronic exposure to an environmental pollutant, dioxin, with harmful effects on health. […]Read more
Professor Vincent Audard (Nephrology and Transplantation Department, IMRB Team 21) as coordinator of the Rare Disease Reference Centre (CRMR) “Idiopathic Nephrotic Syndrome” was presented on Tuesday 12 March 2019 during the Kidney Foundation gala (http://www.fondation-du-rein.org/) a research grant to set up within the 5 CRMR sites (Henri Mondor coordinator site, Robert Débré, Necker, Tenon and […]Read more
Stéphane Palfi, team 14, guest on France Culture of the program “Matières à penser” devoted to “Grands espoirs en médecine”, Friday, February 15, 2019 at 10:15 pm!
Stéphane Palfi, head of Team 14 at our Institute, will be René Frydman’s guest on France Culture’s “Matières à penser” program, dedicated this week to high hopes in medicine and new ideas. He will talk about the promises of stimulating the spinal cord to make paralytics walk again, but also about possible difficulties of experimentation […]Read more
It is around a cake of kings and surrounded by a large number of members of the IMRB, Mrs Camille Chaudonneret our regional delegate of Inserm Paris 6, as well as some members of the Faculty of Medicine, that our director Jorge Boczkowski presented us his wishes and encouragement for this year 2019 which […]Read more
Carbon monoxide-induced metabolic switch in adipocytes improves insulin resistance in obese mice JCI Insight, November 15, 2018
A recent study conducted by Laura Braud, post-doctoral fellow in the Equipe directed by Roberto Motterlini (Equipe 12, IMRB), reveals that carbon monoxide (CO) improves insulin resistance and glucose metabolism in obese mice. The study appeared in the November issue of JCI Insight (Link: https://insight.jci.org/articles/view/123485). Braud and colleagues showed that oral administration of a compound […]Read more
EHVA launches a clinical trial to test a combination of therapeutic vaccines and an immunotherapy drug!
EHVA (European HIV Vaccine Alliance) announces the start of the EHVA T01 / ANRS VRI05 trial. EHVA-T01 / ANRS VRI05, a double-blind, randomized, Phase I/II trial, will evaluate the combination of experimental HIV therapeutic vaccines and an investigational immunotherapy drug in people living with HIV in six European countries – France, Germany, Spain, Italy, […]Read more
Congratulations to Claire Leibler, doctoral student of Team 21, winner of the 2017 Thesis Prize of the University of Paris-Est for ED SVS and the Aguirre/Robin Prize!
Claire Leibler, a nephrologist specializing in kidney transplantation, received the thesis prize from the University of Paris Est for the Doctoral School of Life and Health Sciences (SVS) on November 6. On December 2, she will also receive the Aguirre-Basulado / Robin Prize for Medicine, one of the fifty solemn prizes awarded by the Chancellery […]Read more
Notch-Induced miR-708 Antagonizes Satellite Cell Migration and Maintains Quiescence, 2018,,Cell Stem Cell 23, 1–10, December 6
The majority of adult stem cells are sustained quiescent throughout the lifetime of an organism. A central quest in the stem cell field is to identity the signals that maintain quiescence. Characterization of those signals and their modes of interaction is a major challenge but also a prerequisite for the use of stem cells in […]Read more
Beneficial physical exercise in the treatment of sickle cell disease, a study coordinated by Pablo Bartolucci of Team 2!
According to a recent study coordinated by Pablo Bartolucci of Team 2, with the help of the Department of Public Health and Cardiorespiratory Rehabilitation of CHU Henri Mondor and published in the journal Lancet Haemtology in November 2018, physical exercise would bring definite benefits in the treatment of sickle cell disease. The article appeared in […]Read more
Congratulations to Maximilien Bencze who has just published an article in Nature Communications on the role of necroptosis in the degeneration of dystrophic muscles!
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease, affecting 1 in 5000 live male births and is characterized by a progressive degeneration of myofibres, leading to an irreversible muscle weakness. In DMD, as in many muscle wasting conditions, cell death mechanisms are largely unknown. Within the team 10 directed by Frederic Relaix and Jérôme […]Read more
Interviews with Marion Leboyer, Director of IMRB Team 15 as part of the “Medical/Scientific Interviews”, and for the publication of her latest book “Psychiatry: The State of Emergency”
Marion Leboyer, director of team 15 of the IMRB, the FondaMental Foundation, and head of department at the Chenevier-Mondor hospital in Créteil, has just given an interview as part of the “Entretiens de Médecine/Sciences” conducted jointly by the scientific journal and INSERM. During this interview she talks mainly about the immune system in psychiatry, but […]Read more
Anne-Catherine Bachoud-Lévi, Director of Team 1 at our Institute, and Head of Department at Henri Mondor Hospital, Coordinator of the National Reference Centre – Huntington Disease, was awarded the Légion d’honneur as a knight on July 14. Note the presence in this 2018 promotion of two speakers who came to give (or are about to […]Read more
The British Heart Foundation (BHF) is a UK charity established in 1961 by a group of health professionals to fund additional research into the causes, diagnosis, treatment and prevention of heart and circulatory disease. It is the leading independent funder of cardiovascular research. The BHF Alumni is the free membership program designed to support its […]Read more