Neurofibromatosis and Lymphoma oncogenesis - NFL

Contacts


UNDER DEVELOPMENT – UNDER DEVELOPMENT – UNDER DEVELOPMENT

 

logo_calym_eng

Share

Selected publications

Laurent C, Nicolae A, Laurent C, Le Bras F, Haioun C, Fataccioli V, Amara N, Adélaïde J, Guille A, Schiano JM, Tesson B, Traverse‐Glehen A, Chenard MP, Mescam L, Moreau A, Chassagne‐Clement C, Somja J, Escudié F, André M, Martin N, Lacroix L, Lemonnier F, Hamy‐Petit AS, Reyal F, Bannier M, Oberic L, Prade N, Frénois FX, Beldi‐Ferchiou A, Delfau‐Larue MH, Bouabdallah R, Birnbaum D, Brousset P, Xerri L, Gaulard P. Gene alterations in epigenetic modifiers and JAK‐STAT signaling are frequent in breast implant‐associated ALCL.

Blood. 2020 Jan 30;135(5):360-370.

Drieux F, Ruminy P, Abdel‐Sater A, Lemonnier F, Viailly PJ, Fataccioli V, Machand V, Bisig B, Letourneau A, Parrens M, Bossard C, Bruneau J, Dobay P, Veresezan L, Dupuy A, Pujals A, Robe C, Sako N, Copie‐Bergman C, Delfau‐Larue MH, Picquenot JM, Tilly H, Delarue R, Jardin F, de Leval L, Gaulard P; TENOMIC. Defining the signatures of peripheral T‐cell lymphoma, with a targeted 20‐markers gene expression profiling assay (RT‐MLPA).

Haematologica. 2019 Sep 5. pii: haematol.2019.226647. doi: 10.3324/haematol.2019.226647. [Epub ahead of print]

Radomska KJ, Coulpier F, Gresset A, Schmitt A, Debbiche A, Lemoine S, Wolkenstein P, Vallat JM, Charnay P, Topilko P. Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells.

Cancer Discovery. 2019;9(1):130-147.

Ortonne N, Wolkenstein P, Blakeley JO, Korf B, Plotkin SR, Riccardi VM, Miller DC, Huson S, Peltonen J, Rosenberg A, Carroll SL, Verma SK, Mautner V, Upadhyaya M, Stemmer-Rachamimov A. Cutaneous neurofibromas: Current clinical and pathologic issues.

Neurology. 2018;91(2 Supplement 1):S5-S13

Lemonnier F, Dupuis J, Sujobert P, Tournillhac O, Cheminant M, Sarkozy C, Pelletier L, Marcais A, Robe C, Fataccioli V, Haioun C, Hermine O, Gaulard P, Delarue R. Treatment with 5-azacytidine induces a sustained response in patients with angioimmunoblastic T-cell lymphoma.

Blood 2018;22;132(21):2305-2309.

Vallois D*, Dupuy A*, Lemonnier F, Allen G, Missiaglia E, Fataccioli V, Ortonne N, Clavert A, Delarue R, Rousselet M-C, Fabiani B, Llamas-Gutierrez F, Ogawa S, Thome M, Ko YH, Kataoka K, Gaulard P*, de Leval L*. RNA fusions involving CD28 are rare in peripheral T-Cell lymphomas and concentrate mainly in those derived from follicular helper T cells.

Haematologica 2018;103(8):e360.

Leclaire Alirkilicarslan A, Dupuy A, Pujals A, Parrens M, Vergier B, Robson A, Delfau-Larue M-H, Ingen-Housz-Oro S, Chosidow O, Haioun C, Beylot-Barry M, Merlio J-P, Copie-Bergman C, Gaulard P, Ortonne N. Expression of TFH Markers and Detection of RHOA p.G17V and IDH2 p.R172K/S Mutations in Cutaneous Localizations of Angioimmunoblastic T-Cell Lymphomas.

Am. J. Surg. Pathol. 2017;41:1581–92.

Lemonnier F, Cairns RA, Inoue S, Li WY, Dupuy A, Broutin S, Martin N, Fataccioli V, Pelletier R, Wakeham A, Snow BE, de Leval L, Pujals A, Haioun C, Paci A, Tobin ER, Narayanaswamy R, Yen K, Jin S, Gaulard P, Mak TW. The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.

Proc Natl Acad Sci U S A 2016;113:15084–9.

Vallois D, Dobay MPD, Morin RD, Lemonnier F, Missiaglia E, Juilland M, Iwaszkiewicz J, Fataccioli V, Bisig B, Roberti A, Grewal J, Bruneau J, Fabiani B, Martin A, Bonnet C, Michielin O, Jais J-P, Figeac M, Bernard OA, Delorenzi M, Haioun C, Tournilhac O, Thome M, Gascoyne RD, Gaulard P*, de Leval L*. Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas.

Blood 2016;128:1490–1502.