The British Heart Foundation (BHF) is a UK charity established in 1961 by a group of health professionals to fund additional research into the causes, diagnosis, treatment and prevention of heart and circulatory disease. It is the leading independent funder of cardiovascular research. The BHF Alumni is the free membership program designed to support its […]Read more
Reciprocal signalling by Notch–Collagen V–CALCR retains muscle stem cells in their niche, 2018, Nature, vol 557, pages 714-718
The microenvironment is critical for stem cell maintenance. A central quest in the stem cell field is the composition and source of the molecules that make up their microenvironment. A new study coordinated by Philippos Mourikis (CR1 CNRS) with the participation of Leo Machado (PhD student) in the team of Frederic Relaix (IMRB Team […]Read more
Congratulations to Marion Leboyer, Team 15 Director, who has just received a prestigious award from the ECNP!
Marion Leboyer received the 2018 Neuropsychopharmacology Award of European College of Neuropsychopharmacology (ECNP) in recognition of her outstanding achievements combining innovative and high-impact research identifying genetic and environmental risk factors in major psychiatric disorders. Marion Leboyer will receive the award at the 31st ECNP Congress October 6-9, 2018 in Barcelona, Spain. The prize is […]Read more
Since its creation in 2004, L’Arbre des Connaissances Association founded by researchers has promoted dialogue between scientists and society. The Apprentice Researchers are one of the actions carried out by this association which has enabled more than 2000 secondary school students to be welcomed in the laboratories (more info). This year, under the impetus of […]Read more
Welcome to ORIXHA! New start-up created by the team 3 of Bijan Ghaleh under the impulse of Renaud Tissier!
A start-up called Orixha has just been created under the impulse of Renaud Tissier (Team 03, Bijan Ghaleh) and the help of SATT IDF Innov. This company aims to develop, test and market a liquid fan for ultra-fast induction of hypothermia. The immediate objective is to manufacture a ventilator in compliance with the Medical Devices […]Read more
Congratulations to Geneviève Derumeaux’s team, team 8, for a very interesting article on visceral adipose tissue, heart aging and osteopontin!
Visceral adipose tissue regulates cardiac aging. Osteopontin (OPN) is a matricellular protein that is upregulated in pathologic cardiac fibrosis and remodeling models. OPN plasma levels also increase with age. A new study conducted by Daïgo Sawaki within Team 8, reveals that OPN secreted by visceral adipose tissue (VAT) promotes interstitial fibrosis associated with age […]Read more
The IL4I1 group (Flavia Castellano & Valérie Molinier-Frenkel), on the cover of the last European Journal of Immunology!
Flavia Castellano and Valérie Molinier-Frenkel's group of team 9 (P. Gaulard) with the collaboration of Xavier Decrouy of PL Imaging and Emmanuel Donnadieu of the Cochin Institute has just published an article on the focused secretion of the IL4I1 enzyme at the immune synapse level and its consequences on the activation of T* lymphocytes.Read more
Congratulations to Cyrielle Hou, team 10 of Fred Relaix/François-Jérôme Authier, who has just won the Master’s Award in Myology from the Société Française de Myologie / Santhera Pharmaceuticals!
The Master’s Award in Myology from the French Society of Myology / Santhera Pharmaceuticals is intended to reward a young researcher for the quality of his or her Master’s work in Biology in clinical, physiopathological or fundamental research in the field of Myology. This prize judges the presentation of the thesis and more generally the […]Read more
Congratulations to Carole Hénique of Dil Sahali’s team 21 who has just published an article in Nature Communications on November 28th, 2017!
Rapidly progressive crescent glomerulonephritis (RPGN) is the most aggressive form of acquired glomerular disease. Although most therapeutic approaches use immunosuppressive strategies, pathophysiology is still a mystery.Read more
Congratulations to Mickael Miro-Padovani, Master 2 of Team 7 of A. De La Taille who has just received the jury's special prize for his work directed by Dr Mohamed AmicheRead more
Congratulations B Vingert from F Pirenne team for important paper showing that an anti-CD20 antibody prevents Red Blood Cell alloimmunization in a mouse model!
Congratulations to Benoît Vingert and his colleagues from France Pirenne's team n°2 for his important article in J. Immunology showing that an anti-CD20 antibody prevents the alloimmunization of red blood cells in a murine model. Article included in the Journal of Immunology's editorial of December 1st, 2017!Read more
Very important publication in Fred Relaix team in Cell Reports on the development of a protocol that bypasses the impact of isolation procedures and captures cells in their natural resting state
Léo Machado, Philippos Mourikis and Frederic Relaix (IMRB-U955 team of Fred Relaix) have just published a very important article in the review Cell Reports (IF 8.282) of November 14,2017 on the development of a protocol that bypasses the impact of isolation procedures and captures cells in their natural resting state. Their study also reveals previously […]Read more
Identification of the embryonic origin of FAPs: Team 10 associated with other teams published a very interesting article in Nature Communications (IF: 12.124)
Team 10 of Frédéric Relaix and François-Jérôme Authier associated with several German and French teams, published a very interesting article in the journal Nature Communications on October 31st, 2017. A story that identifies the embryonic origin of FAPs (Fibro-Adipogenic Progenitors), the population of adult muscle mesenchymal stem cells that differentiate into adipocyte and give fibrosis in pathological expectations...Read more
Josselin Houenou and Stéphane Jamain, as well as their colleagues in team 15, have demonstrated a genetic variant associated with both early-onset bipolar disorder and schizophrenia
L’équipe 15 de Marion Leboyer et de Stéphane Jamain a mis en évidence un variant génétique associé à la fois aux troubles bipolaires à début précoce et à la schizophrénie. Les résultats sont publiés dans « The Journal of Neuroscience, 2 October 2017, 1040-17; DOI: https://doi.org/10.1523/JNEUROSCI.1040-17.2017 ». SNAP25 (pour synaptosomal associated protein) est une protéine essentielle […]Read more
The IMRB welcomes applications from outstanding candidates interested in translational research, including basic research and pathophysiology, in preclinical animal models, clinical studies and innovative biotherapy approaches. The candidates should be dynamic and qualified investigators with strong track records, and are expected to apply for competitive funding. Applications from both Junior investigators (to establish a new […]Read more
Erectile dysfunction following treatment for prostate cancer : IMRB at the cutting edge of progress!
After receiving a transplant of stem cells in the penis, 12 patients with severe erectile dysfunction found significant improvements in the quality of sexual intercourseRead more